Structure of PDB 2wt7 Chain A

Receptor sequence
>2wt7A (length=63) Species: 10090 (Mus musculus) [Search protein sequence]
EKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLL
KEKEKLEFILAAH
3D structure
PDB2wt7 Design of a bZIP Transcription Factor with Homo/Heterodimer-Induced DNA-Binding Preference.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A R143 R144 N147 K148 R155 R159 R6 R7 N10 K11 R18 R22
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function

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Biological Process
External links
PDB RCSB:2wt7, PDBe:2wt7, PDBj:2wt7
PDBsum2wt7
PubMed24530283
UniProtP01101|FOS_MOUSE Protein c-Fos (Gene Name=Fos)

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