Structure of PDB 2wre Chain A

Receptor sequence
>2wreA (length=471) Species: 382813 (Influenza A virus (A/Japan/305+/1957(H2N2))) [Search protein sequence]
CIGYHANNSTEKVDTILERNVTVTHAKDILEKTHNGKLCKLNGIPPLELG
DCSIAGWLLGNPECDRLLSVPEWSYIMEKENPRDGLCYPGSFNDYEELKH
LLSSVKHFEKVKILPKDRWTQHTTTGGSQACAVSGNPSFFRNMVLTKKGS
NYPVAKGSYNNTSGEQMLIIWGVHHPIDEKEQRTLYQNVGTYVSVGTSTL
NKRSTPEIATRPKVNGLGSRMEFSWTLLDMWDTINFESTGNLIAPEYGFK
ISKRGSSGIMKTEGTLENCETKCQTPLGAINTTLPFHNVHPLTIGECPKY
VKSEKLVLATGLRNVPQGLFGAIAGFIEGGWQGMVDGWYGYHADKESTQK
AFDGITNKVNSVIEKMNTQFEAVGKEFSNLERRLENLNKKMEDGFLDVWT
YNAELLVLMENERTLDFHDSNVKNLYDKVRMQLRDNVKELGNGCFEFYHK
CDDECMNSVKNGTYDYPKYEE
3D structure
PDB2wre From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
ChainA
Resolution3.001 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA A Y95 G134 S135 H182 E189 L193 S227 Y88 G127 S128 H174 E181 L185 S219
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019062 virion attachment to host cell
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046718 symbiont entry into host cell
GO:0046761 viral budding from plasma membrane
GO:0075512 clathrin-dependent endocytosis of virus by host cell
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0019031 viral envelope
GO:0020002 host cell plasma membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2wre, PDBe:2wre, PDBj:2wre
PDBsum2wre
PubMed19805083
UniProtQ0A2X3

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