Structure of PDB 2wr7 Chain A

Receptor sequence
>2wr7A (length=473) Species: 382781 (Influenza A virus (A/Singapore/1/1957(H2N2))) [Search protein sequence]
IGYHANNSTEKVDTILERNVTVTHAKDILEKTHNGKLCKLNGIPPLELGD
CSIAGWLLGNPECDRLLSVPEWSYIMEKENPRDGLCYPGSFNDYEELKHL
LSSVKHFEKVKILPKDRWTQHTTTGGSRACAVSGNPSFFRNMVLTEKGSN
YPVAKGSYNNTSGEQMLIIWGVHHPNDETEQRTLYQNVGTYVSVGTSTLN
KRSTPDIATRPKVNGLGSRMEFSWTLLDMWDTINFESTGNLIAPEYGFKI
SKRGSSGIMKTEGTLENCETKCQTPLGAINTTLPFHNVHPLTIGECPKYV
KSEKLVLATGLRNVPGLFGAIAGFIEGGWQGMIDGWYGYHHSNDQGSGYA
ADKESTQKAFDGITNKVNSVIEKMNTQFEAVGKEFSNLERRLENLNKKME
DGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRMQLRDNVKELGN
GCFEFYHKCDDECMNSVKNGTYD
3D structure
PDB2wr7 From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA A Y95 G134 S135 H182 E189 L193 S227 Y87 G126 S127 H173 E180 L184 S218
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2wr7, PDBe:2wr7, PDBj:2wr7
PDBsum2wr7
PubMed19805083
UniProtQ67333|HEMA_I57A5 Hemagglutinin (Gene Name=HA)

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