Structure of PDB 2wm3 Chain A

Receptor sequence
>2wm3A (length=296) Species: 9606 (Homo sapiens) [Search protein sequence]
DKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKELRLQGA
EVVQGDQDDQVIMELALNGAYATFIVTNYWESCSQEQEVKQGKLLADLAR
RLGLHYVVYSGLENIKKLTAGRLAAAHFDGKGEVEEYFRDIGVPMTSVRL
PCYFENLLSHFLPQKAPDGKSYLLSLPTGDVPMDGMSVSDLGPVVLSLLK
MPEKYVGQNIGLSTCRHTAEEYAALLTKHTRKVVHDAKMTPEDYEKLGFP
GARDLANMFRFYALRPDRDIELTLRLNPKALTLDQWLEQHKGDFNL
3D structure
PDB2wm3 Crystal Structure of Nmra-Like Family Domain Containing Protein 1 in Complex with Niflumic Acid
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NAP A G11 T13 G14 A15 Q16 T36 R37 K41 D58 Q59 T79 N80 K133 Y155 N158 G9 T11 G12 A13 Q14 T34 R35 K39 D56 Q57 T77 N78 K131 Y153 N156
BS02 NFL A W82 H129 H162 M260 Y264 W80 H127 H160 M258 Y262
BS03 NFL A L120 F263 L266 L118 F261 L264
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0042802 identical protein binding
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0048471 perinuclear region of cytoplasm

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Molecular Function

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Cellular Component
External links
PDB RCSB:2wm3, PDBe:2wm3, PDBj:2wm3
PDBsum2wm3
PubMed
UniProtQ9HBL8|NMRL1_HUMAN NmrA-like family domain-containing protein 1 (Gene Name=NMRAL1)

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