Structure of PDB 2wkh Chain A

Receptor sequence
>2wkhA (length=244) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
SITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARASKEYLPASTFC
IPNAIIGLETGVIKNEHQVFKWDGKPRAMKQWERDLTLRGAIQVSAVPVF
QQIAREVGEVRMQKYLKKFSYGNQNISGGIDKFWLEGQLRISAVNQVEFL
ESLYLNKLSASKENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVA
WWVGWVEKETEVYFFAFNMDIDNESKLPLRKSIPTKIMESEGII
3D structure
PDB2wkh Three Factors that Modulate the Activity of Class D Beta-Lactamases and Interfere with the Post-Translational Carboxylation of Lys70.
ChainA
Resolution1.791 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S67 C70 S115 F120 W154 F208
Catalytic site (residue number reindexed from 1) S47 C50 S95 F100 W134 F188
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZZ7 A S67 W102 S115 F208 R250 S47 W82 S95 F188 R230
Gene Ontology
Molecular Function
GO:0008658 penicillin binding

View graph for
Molecular Function
External links
PDB RCSB:2wkh, PDBe:2wkh, PDBj:2wkh
PDBsum2wkh
PubMed21108605
UniProtP14489|BLO10_PSEAI Beta-lactamase OXA-10 (Gene Name=bla)

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