Structure of PDB 2whm Chain A

Receptor sequence
>2whmA (length=377) Species: 155077 (Cellvibrio japonicus) [Search protein sequence]
KPVTVKLVDSQATMETRSLFAFMQEQRRHSIMFGHQHETTQGLTITRTDG
TQSDTFNAVGDFAAVYGWDTLSIVAPKAAGDIVAQVKKAYARGGIITVSS
HFDNPKTDTQKGVWPVGTSWDQTPAVVDSLPGGAYNPVLNGYLDQVAEWA
NNLKDEQGRLIPVIFRLYHENTGSWFWWGDKQSTPEQYKQLFRYSVEYLR
DVKGVRNFLYAYSPNNFWDVTEANYLERYPGDEWVDVLGFDTYGPVADNA
DWFRNVVANAALVARMAEARGKIPVISGIGIRAPDIEAGLYDNQWYRKLI
SGLKADPDAREIAFLLVWRNAPQGVPGQVPHYWVPANRPENINNGTLEDF
QAFYADEFTAFNRDIEQVYQRPTLIVK
3D structure
PDB2whm Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates.
ChainA
Resolution1.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.2.1.78: mannan endo-1,4-beta-mannosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN A H143 E212 Y285 W360 W379 H101 E170 Y243 W318 W333
BS02 BMA A W162 W360 R361 H377 W120 W318 R319 H331
BS03 ZN A E67 H71 E25 H29
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016787 hydrolase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0016985 mannan endo-1,4-beta-mannosidase activity
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0006080 substituted mannan metabolic process
GO:0010391 glucomannan metabolic process
GO:0051069 galactomannan metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2whm, PDBe:2whm, PDBj:2whm
PDBsum2whm
PubMed19441796
UniProtP49424|MANA_CELJU Mannan endo-1,4-beta-mannosidase (Gene Name=manA)

[Back to BioLiP]