Structure of PDB 2wfj Chain A

Receptor sequence
>2wfjA (length=172) Species: 9606 (Homo sapiens) [Search protein sequence]
QRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQ
KPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHN
KEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIE
NQKTDAASKPFAEVRILSCGEL
3D structure
PDB2wfj The Thermodynamic Influence of Trapped Water Molecules on a Protein-Ligand Interaction.
ChainA
Resolution0.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R67 F72 Q75 N114 F125 L134 H138
Catalytic site (residue number reindexed from 1) R62 F67 Q70 N109 F120 L129 H133
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R67 F72 Q75 G84 A113 N114 R115 Q123 F125 H133 H138 R62 F67 Q70 G79 A108 N109 R110 Q118 F120 H128 H133
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:2wfj, PDBe:2wfj, PDBj:2wfj
PDBsum2wfj
PubMed19499554
UniProtQ13427|PPIG_HUMAN Peptidyl-prolyl cis-trans isomerase G (Gene Name=PPIG)

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