Structure of PDB 2wb2 Chain A

Receptor sequence
>2wb2A (length=508) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
DSQRSTLVHWFRKGLRLHDNPALSHIFTAANAAPGRYFVRPIFILDPGIL
DWMQVGANRWRFLQQTLEDLDNQLRKLNSRLFVVRGKPAEVFPRIFKSWR
VEMLTFETDIEPYSVTRDAAVQKLAKAEGVRVETHCSHTIYNPELVIAKN
LGKAPITYQKFLGIVEQLKVPKVLGVPEKLKNMPTPPKDEVEQKDSAAYD
CPTMKQLVKRPEELGPNKFPGGETEALRRMEESLKDEIWVARFEKPNTAP
NSLEPSTTVLSPYLKFGCLSARLFNQKLKEIIKRQPKHSQPPVSLIGQLM
WREFYYTVAAAEPNFDRMLGNVYCMQIPWQEHPDHLEAWTHGRTGYPFID
AIMRQLRQEGWIHHLARHAVACFLTRGDLWISWEEGQRVFEQLLLDQDWA
LNAGNWMWLSASAFFHQYFRVYSPVAFGKKTDPQGHYIRKYVPELSKYPA
GCIYEPWKASLVDQRAYGCVLGTDYPHRIVKHEVVHKENIKRMGAAYKVN
REVRTGKE
3D structure
PDB2wb2 Crystal Structure of the T(6-4)C Lesion in Complex with a (6-4) DNA Photolyase and Repair of Uv- Induced (6-4) and Dewar Photolesions.
ChainA
Resolution2.95 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q299 W302 W330 H365 W384 W407
Catalytic site (residue number reindexed from 1) Q298 W301 W329 H364 W383 W406
Enzyme Commision number 4.1.99.3: deoxyribodipyrimidine photo-lyase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003904 deoxyribodipyrimidine photo-lyase activity
GO:0071949 FAD binding
Biological Process
GO:0032922 circadian regulation of gene expression
GO:0043153 entrainment of circadian clock by photoperiod
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2wb2, PDBe:2wb2, PDBj:2wb2
PDBsum2wb2
PubMed19722240
UniProtQ8SXK5

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