Structure of PDB 2w92 Chain A

Receptor sequence
>2w92A (length=635) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence]
TLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASK
EAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPD
VIDAGHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVD
MAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSW
YDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWDKAKNDYT
IATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFA
PDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRT
PAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTST
GEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLR
VAHKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAG
KTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKN
AQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIYLPKVSRSAS
AQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKD
3D structure
PDB2w92 Streptococcus Pneumoniae Endohexosaminidase D, Structural and Mechanistic Insight Into Substrate-Assisted Catalysis in Family 85 Glycoside Hydrolases.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NGT A W264 F333 N335 Y373 F412 E441 F471 W92 F161 N163 Y201 F240 E269 F299 MOAD: Kd=28uM
PDBbind-CN: -logKd/Ki=4.55,Kd=28uM
Gene Ontology
Molecular Function
GO:0033925 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:2w92, PDBe:2w92, PDBj:2w92
PDBsum2w92
PubMed19181667
UniProtQ93HW0

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