Structure of PDB 2w3g Chain A

Receptor sequence
>2w3gA (length=150) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
GAMDPDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEET
VRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLG
VPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQ
3D structure
PDB2w3g Structural Insight Into the Heme-Based Redox Sensing by Doss from Mycobacterium Tuberculosis.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM A Y83 F98 Y100 I103 H113 P115 K116 G119 V120 S142 I143 G144 F145 P146 H149 M152 Y26 F41 Y43 I46 H56 P58 K59 G62 V63 S85 I86 G87 F88 P89 H92 M95
External links
PDB RCSB:2w3g, PDBe:2w3g, PDBj:2w3g
PDBsum2w3g
PubMed19276084
UniProtP9WGK3|DEVS_MYCTU Oxygen sensor histidine kinase response regulator DevS/DosS (Gene Name=devS)

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