Structure of PDB 2w3f Chain A

Receptor sequence
>2w3fA (length=148) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
GAMDPDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEET
VRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLG
VPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARL
3D structure
PDB2w3f Structural Insight Into the Heme-Based Redox Sensing by Doss from Mycobacterium Tuberculosis.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM A G84 A85 F98 Y100 I103 H113 P115 K116 G119 S142 I143 G144 F145 P146 H149 M152 F155 Y171 T173 G27 A28 F41 Y43 I46 H56 P58 K59 G62 S85 I86 G87 F88 P89 H92 M95 F98 Y114 T116
External links
PDB RCSB:2w3f, PDBe:2w3f, PDBj:2w3f
PDBsum2w3f
PubMed19276084
UniProtP9WGK3|DEVS_MYCTU Oxygen sensor histidine kinase response regulator DevS/DosS (Gene Name=devS)

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