Structure of PDB 2w3d Chain A

Receptor sequence
>2w3dA (length=148) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
GAMDPDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEET
VRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLG
VPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARL
3D structure
PDB2w3d Structural Insight Into the Heme-Based Redox Sensing by Doss from Mycobacterium Tuberculosis.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A Y83 F98 I103 V108 I111 H113 P115 K116 G117 L118 G119 V120 S142 I143 F145 P146 H149 M152 Y171 Y26 F41 I46 V51 I54 H56 P58 K59 G60 L61 G62 V63 S85 I86 F88 P89 H92 M95 Y114
External links
PDB RCSB:2w3d, PDBe:2w3d, PDBj:2w3d
PDBsum2w3d
PubMed19276084
UniProtP9WGK3|DEVS_MYCTU Oxygen sensor histidine kinase response regulator DevS/DosS (Gene Name=devS)

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