Structure of PDB 2w0z Chain A
Receptor sequence
>2w0zA (length=58) Species:
9606
(Homo sapiens) [
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GPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFP
RNYVTAVN
3D structure
PDB
2w0z
Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Chain
A
Resolution
1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
A
F7 F9 Q12 E16 D32 W35 P48 N50 Y51
F9 F11 Q14 E18 D34 W37 P50 N52 Y53
External links
PDB
RCSB:2w0z
,
PDBe:2w0z
,
PDBj:2w0z
PDBsum
2w0z
PubMed
19523899
UniProt
P62993
|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)
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