Structure of PDB 2w0z Chain A

Receptor sequence
>2w0zA (length=58) Species: 9606 (Homo sapiens) [Search protein sequence]
GPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFP
RNYVTAVN
3D structure
PDB2w0z Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A F7 F9 Q12 E16 D32 W35 P48 N50 Y51 F9 F11 Q14 E18 D34 W37 P50 N52 Y53
External links
PDB RCSB:2w0z, PDBe:2w0z, PDBj:2w0z
PDBsum2w0z
PubMed19523899
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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