Structure of PDB 2vzw Chain A

Receptor sequence
>2vzwA (length=146) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
GKLDATLRAIVHTAAELVDARYGALGVRGYDHRLVEFVYEGIDEETRHLI
GSLPEGRGVLGALIEEPKPIRLDDISRHPASVGFPLHHPPMRTFLGVPVR
IRDEVFGNLYLTEKADGQPFSDDDEVLVQALAAAAGIAVDNARLFE
3D structure
PDB2vzw 2.3 A X-Ray Structure of the Heme-Bound Gaf Domain of Sensory Histidine Kinase Dost of Mycobacterium Tuberculosis.
ChainA
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A Y81 E99 R106 I109 S111 L112 P113 E114 G115 G117 S140 V141 F143 H147 M150 F153 Y169 Y22 E40 R47 I50 S52 L53 P54 E55 G56 G58 S81 V82 F84 H88 M91 F94 Y110
External links
PDB RCSB:2vzw, PDBe:2vzw, PDBj:2vzw
PDBsum2vzw
PubMed18980385
UniProtP9WGK1|DOST_MYCTU Oxygen sensor histidine kinase response regulator DosT (Gene Name=dosT)

[Back to BioLiP]