Structure of PDB 2vur Chain A

Receptor sequence
>2vurA (length=584) Species: 1502 (Clostridium perfringens) [Search protein sequence]
VLVPNLNPTPENLEVVGDGFKITSSINLVGEEEADENAVNALREFLTANN
IEINSENDPNSTTLIIGEVDDDIPELDEALNGTTAENLKEEGYALVSNDG
KIAIEGKDGDGTFYGVQTFKQLVKESNIPEVNITDYPTVSARGIVEGFYG
TPWTHQDRLDQIKFYGENKLNTYIYAPKDDPYHREKWREPYPESEMQRMQ
ELINASAENKVDFVFGISPGIDIRFDGDAGEEDFNHLITKAESLYDMGVR
SFAIYWDDIQDKSAAKHAQVLNRFNEEFVKAKGDVKPLITVPTEYDTGAM
VSNGQPRAYTRIFAETVDPSIEVMWTGPGVVTNEIPLSDAQLISGIYNRN
MAVWWNYPVTDYFKGKLALGPMHGLDKGLNQYVDFFTVNPMEHAELSKIS
IHTAADYSWNMDNYDYDKAWNRAIDMLYGDLAEDMKVFANHSTRMDNKTW
AKSGREDAPELRAKMDELWNKLSSKEDASALIEELYGEFARMEEACNNLK
ANLPEVALEECSRQLDELITLAQGDKASLDMIVAQLNEDTEAYESAKEIA
QNKLNTALSSFAVISEKVAQSFIQEALSFDLTLI
3D structure
PDB2vur Chemical Dissection of the Link between Streptozotocin, O-Glcnac, and Pancreatic Cell Death.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.169: protein O-GlcNAcase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YX1 A G187 D297 V331 Y335 V370 W394 D401 G147 D257 V291 Y295 V330 W354 D361 MOAD: ic50=30uM
PDBbind-CN: -logKd/Ki=4.52,IC50=30uM
External links
PDB RCSB:2vur, PDBe:2vur, PDBj:2vur
PDBsum2vur
PubMed18721751
UniProtQ0TR53|OGA_CLOP1 O-GlcNAcase NagJ (Gene Name=nagJ)

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