Structure of PDB 2vr0 Chain A

Receptor sequence

>2vr0A (length=495) Species: 882 (Nitratidesulfovibrio vulgaris str. Hildenborough) [Search protein sequence]

GCSDVSTELKTPVYKTKLTAEEIRNSAFKPEFPKQYASYERNDETTVMTE
YKGSVPFNKNDNVNPLPEGYRHAQPYLKNLWLGYPFMYEYREARGHTYAI
QDFLHIDRINRYAEKGGLPATCWNCKTPKMMEWVKESGDGFWAKDVNEFR
DKIDMKDHTIGCATCHDPQTMELRITSVPLTDYLVSQGKDPKKLPRNEMR
ALVCGQCHVEYYFNGPTMGVNKKPVFPWAEGFDPADMYRYYDKHGDLQVK
GFEGKFADWTHPASKTPMIKAQHPEYETWINGTHGAAGVTCADCHMSYTR
SDDKKKISSHWWTSPMKDPEMRACRQCHSDKTPDYLKSRVLFTQKRTFDL
LLAAQEVSVKAHEAVRLANEYQGAKAAGYDDLMIQAREMVRKGQFFWDYV
SAENSVGFHNPAKALDTLAQSQQFSQKAIDLAMEATQYGIGKDLSGDIKT
IVPPILKMNRKLQQDPEFMKTHKWFQYLPVLPKADQVWDGQKRLV

3D structure

PDB

2vr0 Quinol Oxidation by C-Type Cytochromes: Structural Characterization of the Menaquinol Binding Site of Nrfha.

Chain

Resolution

2.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.7.2.2: nitrite reductase (cytochrome; ammonia-forming).

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	HEC	A	R116 A118 I131 R133 C147 C150 K151 C232 H233 Y236 H298 N429	R91 A93 I106 R108 C122 C125 K126 C207 H208 Y211 H273 N404
BS02	HEC	A	Y39 F57 Q60 Y64 G186 C187 C190 H191 L198 R221 M321 I332 S333 H335 W337	Y14 F32 Q35 Y39 G161 C162 C165 H166 L173 R196 M296 I307 S308 H310 W312
BS03	HEC	A	S79 R119 G120 H121 Y123 A124 D127 C150 I185 T189 C229 C232 H233 H320 W337 T338	S54 R94 G95 H96 Y98 A99 D102 C125 I160 T164 C204 C207 H208 H295 W312 T313
BS04	HEC	A	T74 K77 G78 E117 H233 W304 H309 V314 T315 C316 C319 H320 S339 M341 Q369 N429 F433 H434	T49 K52 G53 E92 H208 W279 H284 V289 T290 C291 C294 H295 S314 M316 Q344 N404 F408 H409
BS05	HEC	A	H309 C349 C352 H353 F433	H284 C324 C327 H328 F408
BS06	CA	A	E235 Y236 K295 A296 Q297	E210 Y211 K270 A271 Q272
BS07	CA	A	G78 E117 A118	G53 E92 A93
BS08	HEC	A	H353 K356	H328 K331
BS09	HEC	A	Y323 R325 K331 R347 Q351	Y298 R300 K306 R322 Q326

Gene Ontology

	Molecular Function
GO:0042279	nitrite reductase (cytochrome, ammonia-forming) activity

	Cellular Component
GO:0042597	periplasmic space

View graph for
Molecular Function

View graph for
Cellular Component

External links

PDB	RCSB:2vr0, PDBe:2vr0, PDBj:2vr0
PDBsum	2vr0
PubMed	18597779
UniProt	Q72EF3\|NRFA_NITV2 Cytochrome c nitrite reductase subunit NrfA (Gene Name=nrfA)

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