Structure of PDB 2vkq Chain A

Receptor sequence
>2vkqA (length=273) Species: 9606 (Homo sapiens) [Search protein sequence]
NPTRVEEIICGLIKGGAAKLQIITDFDMTLSRFSYKGKRCPTCHNIIDNC
KLVTDECRKKLLQLKEKYYAIEVDPVLTVEEKYPYMVEWYTKSHGLLVQQ
ALPKAKLKEIVAESDVMLKEGYENFFDKLQQHSIPVFIFSAGIGDVLEEV
IRQAGVYHPNVKVVSNFMDFDETGVLKGFKGELIHVFNKHDGALRNTEYF
NQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYLNDRVDELLEKYMD
SYDIVLVQDESLEVANSILQKIL
3D structure
PDB2vkq Crystal Structure of Human Cytosolic 5'- Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.5: 5'-nucleotidase.
3.1.3.91: 7-methylguanosine nucleotidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BEF A D38 F39 D40 S153 A154 K202 D25 F26 D27 S140 A141 K189
BS02 MG A D38 D40 D227 D25 D27 D214
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0008253 5'-nucleotidase activity
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:2vkq, PDBe:2vkq, PDBj:2vkq
PDBsum2vkq
PubMed
UniProtQ9H0P0|5NT3A_HUMAN Cytosolic 5'-nucleotidase 3A (Gene Name=NT5C3A)

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