Structure of PDB 2vfk Chain A

Receptor sequence
>2vfkA (length=205) Species: 9606 (Homo sapiens) [Search protein sequence]
YQPNYFLSIPITNKKITAGIKVLQNSILRQDNRLTKAMVGDGSFHITLLV
MQLLNEDEVNIGTDALLELKPFVEEILEGKHLTLPFHGIGTFQGQVGFVK
LADGDHVSALLEIAETAKRTFQEKGILAGESRTFKPHLTFMKLSKAPMLW
KKGVRKIEPGLYEQFIDHRFGEEILYQIDLCSMLKKKQSNGYYHCESSIV
IGEKD
3D structure
PDB2vfk Akap18 Contains a Phosphoesterase Domain that Binds AMP
ChainA
Resolution1.5 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AMP A T134 F179 R219 H224 T226 T47 F92 R132 H137 T139 MOAD: Kd=194uM
PDBbind-CN: -logKd/Ki=3.71,Kd=194uM
External links