Structure of PDB 2vdy Chain A

Receptor sequence
>2vdyA (length=361) Species: 9606 (Homo sapiens) [Search protein sequence]
GLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRA
QLLQGLGFNLSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELL
ESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFDSPA
ILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYL
HDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLT
SSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTTQANFSRITQDAQLKSS
KVVHKAVLQLNEEGTEAAGAMFLEAIPRKPIILRFNQPFIIMIFDHFTWS
SLFLARVMNPV
3D structure
PDB2vdy The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release.
ChainA
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HCY A S19 Q232 I263 N264 S267 F366 H368 W371 S4 Q211 I242 N243 S246 F344 H346 W349 BindingDB: Ki=13nM
Gene Ontology
Molecular Function
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005496 steroid binding
Biological Process
GO:0008211 glucocorticoid metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0070062 extracellular exosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2vdy, PDBe:2vdy, PDBj:2vdy
PDBsum2vdy
PubMed18513745
UniProtP08185|CBG_HUMAN Corticosteroid-binding globulin (Gene Name=SERPINA6)

[Back to BioLiP]