Structure of PDB 2vcb Chain A

Receptor sequence
>2vcbA (length=882) Species: 1502 (Clostridium perfringens) [Search protein sequence]
GVEITEGVTVTAKGNTEGNTADLAIDGDLSTYWESSNDYKWIEVDLGGIY
ELSKIEIFNKDEAVYKYNIYASEDGENFNKIAYKNNDNVSDSNGNMHTID
NVRAGKIRIDVVQNSNSDRVNIAEINVFGKNTGESLPEKKIATSNFSETP
WATEYEKFNSDSAYANEKTLNEIKNLVGRVIGREFKDKFIFEIRDQLNGN
DVFEVSDSGDGKVLIKGNNGVSLASGFNYYLKNYCNVSYNPIMGSNLKMP
ETMPSVGERVVIDTPYEHRYALNFCTYSYTMSFWDWDQYEEFLDWCAMNG
VNLVLDIIGQEEVLRRTLNEFGYSDEEVKEFISGPAYFAWFYMQNMTGFG
GPLPNDWFEQRAELGRKMHDRMQSFGINPVLQGYSGMVPRDFKEKNQEAQ
TISQGGWCGFDRPDMLKTYVNEGEADYFQKVADVFYEKQKEVFGDVTNFY
GVDPFHEGGNTGDLDNGKIYEIIQNKMIEHDNDAVWVIQNWQGNPSNNKL
EGLTKKDQAMVLDLFSEVSPDWNRLEERDLPWIWNMLHNFGGRMGMDAAP
EKLATEIPKALANSEHMVGIGITPEAINTNPLAYELLFDMAWTRDQINFR
TWTEDYIERRYGKTNKEILEAWNIILDTAYKKRNDYYQGAAESIINARPG
FGIKSASTWGHSKIVYDKSEFEKAIEIFAKNYDEFKDSDAFLYDFADILK
QLLANSAQEYYEVMCNAYNNGNGEKFKFVSGKFLELIKLQERVLSTRPEF
LIGNWIEDARTMLKDSDDWTKDLFEFNARALVTTWGSRNNADGGGLKDYS
NRQWSGLTEDYYYARWEKWINGLQAELDGAKAPNIDWFKMEYDWVNKKSD
TDKLYPTEASNENLGELAKIAMESYSVTNMDK
3D structure
PDB2vcb Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.50: alpha-N-acetylglucosaminidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OAN A C301 Y305 W366 M369 H482 E483 W517 F566 E601 Q664 W685 Y825 K909 C275 Y279 W340 M343 H456 E457 W491 F540 E575 Q638 W659 Y799 K882 PDBbind-CN: -logKd/Ki=5.26,Kd=5.5uM
BS02 CA A L48 D51 D53 T56 A148 E149 L23 D26 D28 T31 A123 E124
External links