Structure of PDB 2v7o Chain A

Receptor sequence
>2v7oA (length=306) Species: 9606 (Homo sapiens) [Search protein sequence]
TENLYFQSMATCTRFTDDYQLFEELGKGFSVVRRCVKKTPTQEYAAKIIN
TKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG
ELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLAS
KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVD
IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAK
NLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNA
RRKLKG
3D structure
PDB2v7o Structure of the Camkiidelta/Calmodulin Complex Reveals the Molecular Mechanism of Camkii Kinase Activation.
ChainA
Resolution2.25 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D136 K138 N141 D157 T177
Catalytic site (residue number reindexed from 1) D140 K142 N145 D161 T181
Enzyme Commision number 2.7.11.17: calcium/calmodulin-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DRN A L20 G21 V28 A41 F90 D91 L92 V93 D157 L25 G26 V32 A45 F94 D95 L96 V97 D161
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2v7o, PDBe:2v7o, PDBj:2v7o
PDBsum2v7o
PubMed20668654
UniProtQ13555|KCC2G_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit gamma (Gene Name=CAMK2G)

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