Structure of PDB 2uwe Chain A

Receptor sequence
>2uweA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGACVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB2uwe Single Mhc Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 E63 K66 V67 A69 H70 T73 D77 Y84 Y99 Y116 T143 W147 L156 Y159 W167 Y171 Y7 E63 K66 V67 A69 H70 T73 D77 Y84 Y99 Y116 T143 W147 L156 Y159 W167 Y171
External links
PDB RCSB:2uwe, PDBe:2uwe, PDBj:2uwe
PDBsum2uwe
PubMed17825839
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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