Structure of PDB 2uv6 Chain A

Receptor sequence
>2uv6A (length=143) Species: 9606 (Homo sapiens) [Search protein sequence]
HEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPV
VDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCY
LHETLETIINRLVEAEVHQLVVVDENDVVKGIVSLSDILQALV
3D structure
PDB2uv6 Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AMP A T200 I204 A205 V225 S226 A227 I312 S314 S316 D317 V323 T20 I24 A25 V45 S46 A47 I132 S134 S136 D137 V143
External links
PDB RCSB:2uv6, PDBe:2uv6, PDBj:2uv6
PDBsum2uv6
PubMed17452784
UniProtP54619|AAKG1_HUMAN 5'-AMP-activated protein kinase subunit gamma-1 (Gene Name=PRKAG1)

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