Structure of PDB 2rve Chain A

Receptor sequence
>2rveA (length=213) Species: 562 (Escherichia coli) [Search protein sequence]
SLRSDLINALYYDVCGIISAEGKIYPLGSDTKVLSTIFELFSRPIINKIA
EKHGYIVEEPKQQNHYPDFTLYKPSEPNKKIAIDIKTTYTNKENEKIKFT
LGGYTSFIRNNTKNIVYPFDQYIAHWIIGYVYTRTYNINELNEIPKPYKG
VKVFLQDKWVIAGDLAGSTNIGSIHAHYKDFVEGKGIFDSEDEFLDYWRN
YEYNNISEYRNWI
3D structure
PDB2rve The crystal structure of EcoRV endonuclease and of its complexes with cognate and non-cognate DNA fragments.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A T37 T106 R140 N188 T31 T100 R134 N170
BS02 dna A Q68 Q69 N70 Q62 Q63 N64
BS03 dna A S112 N120 S106 N114
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:2rve, PDBe:2rve, PDBj:2rve
PDBsum2rve
PubMed8491171
UniProtP04390|T2E5_ECOLX Type II restriction enzyme EcoRV (Gene Name=ecoRVR)

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