Structure of PDB 2rqc Chain A

Receptor sequence
>2rqcA (length=115) Species: 9606 (Homo sapiens) [Search protein sequence]
GSSGSSGLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFG
NVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQ
LKRSKNDSKSGPSSG
3D structure
PDB2rqc Structural basis for the sequence-specific RNA-recognition mechanism of human CUG-BP1 RRM3
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A Q394 F404 Y406 Q410 S429 A430 K431 F433 I434 K436 K442 F446 S448 K473 K477 R478 Q19 F29 Y31 Q35 S54 A55 K56 F58 I59 K61 K67 F71 S73 K98 K102 R103 PDBbind-CN: Kd=1.9uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:2rqc, PDBe:2rqc, PDBj:2rqc
PDBsum2rqc
PubMed19553194
UniProtQ92879|CELF1_HUMAN CUGBP Elav-like family member 1 (Gene Name=CELF1)

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