Structure of PDB 2rl8 Chain A

Receptor sequence
>2rl8A (length=148) Species: 9913 (Bos taurus) [Search protein sequence]
KTCDLVGEKGKESEKELALLKRLTPLFQKSFESTVGDMYSYVFRVCREAG
QHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEYDNHC
GREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS
3D structure
PDB2rl8 Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor.
ChainA
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M6D A Y45 Q66 Y102 D103 N104 H105 R111 E133 R135 Y143 Y39 Q60 Y96 D97 N98 H99 R105 E127 R129 Y137
Gene Ontology
Molecular Function
GO:0019904 protein domain specific binding
Biological Process
GO:0006622 protein targeting to lysosome
Cellular Component
GO:0005768 endosome
GO:0005794 Golgi apparatus

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Cellular Component
External links
PDB RCSB:2rl8, PDBe:2rl8, PDBj:2rl8
PDBsum2rl8
PubMed18272523
UniProtP11456|MPRD_BOVIN Cation-dependent mannose-6-phosphate receptor (Gene Name=M6PR)

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