Structure of PDB 2ria Chain A

Receptor sequence
>2riaA (length=146) Species: 9606 (Homo sapiens) [Search protein sequence]
QVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQL
LCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMTDSKTEGKFTYPTG
ESLVYSNWAPGEPNDDGGSEDCVEIFTNGKWNDRACGEKRLVVCEF
3D structure
PDB2ria Recognition of heptoses and the inner core of bacterial lipopolysaccharides by surfactant protein d.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A E321 N323 E329 N341 D342 E112 N114 E120 N132 D133
BS02 CA A D297 E301 D324 E329 D330 D88 E92 D115 E120 D121
BS03 CA A E301 D330 E92 D121
BS04 289 A E321 N323 E329 N341 R343 E112 N114 E120 N132 R134 MOAD: ic50=2.7mM
PDBbind-CN: -logKd/Ki=2.57,IC50=2.7mM
External links
PDB RCSB:2ria, PDBe:2ria, PDBj:2ria
PDBsum2ria
PubMed18092821
UniProtP35247|SFTPD_HUMAN Pulmonary surfactant-associated protein D (Gene Name=SFTPD)

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