Structure of PDB 2rgg Chain A

Receptor sequence
>2rggA (length=159) Species: 9606 (Homo sapiens) [Search protein sequence]
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGET
CLLDILDTAGRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSD
DVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFY
TLVREIRQH
3D structure
PDB2rgg Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf.
ChainA
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A S17 T35 S17 T35
BS02 GNP A G13 G15 K16 S17 A18 F28 V29 T35 G60 N116 K117 D119 L120 S145 A146 G13 G15 K16 S17 A18 F28 V29 T35 G60 N109 K110 D112 L113 S138 A139
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2rgg, PDBe:2rgg, PDBj:2rgg
PDBsum2rgg
PubMed18073111
UniProtP01112|RASH_HUMAN GTPase HRas (Gene Name=HRAS)

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