Structure of PDB 2reg Chain A

Receptor sequence
>2regA (length=290) Species: 266834 (Sinorhizobium meliloti 1021) [Search protein sequence]
EPESCGTVRFSDVGWTDITATTATATTILEALGYETDVKVLSVPVTYTSL
KNKDIDVFLGNWMPTMEADIAPYREDKSVETVRENLAGAKYTLATNAKGA
ELGIKDFKDIAAHKDELDGKIYGIEPGNDGNRLIIDMVEKGTFDLKGFEV
VESSEQGMLAQVARAEKSGDPIVFLGWEPHPMNANFKLTYLSGGDDVFGP
NYGGATVHTNVRAGYTTECPNVDKLLQNLSFSLQMENEIMGKILNDGEDP
EKAAAAWLKDNPQSIEPWLSGVATKDGGDGLAAVKAALGL
3D structure
PDB2reg Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CHT A W43 W90 Y119 N156 D157 W205 W15 W62 Y91 N128 D129 W177 MOAD: Kd=2.3uM
PDBbind-CN: -logKd/Ki=5.64,Kd=2.3uM
Gene Ontology
Molecular Function
GO:0022857 transmembrane transporter activity
GO:0033265 choline binding
Biological Process
GO:0015871 choline transport
GO:0055085 transmembrane transport
Cellular Component
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2reg, PDBe:2reg, PDBj:2reg
PDBsum2reg
PubMed18779321
UniProtQ92N37

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