Structure of PDB 2rds Chain A

Receptor sequence
>2rdsA (length=261) Species: 33903 (Streptomyces avermitilis) [Search protein sequence]
TGDYTDCTPLLGDRAALDSFYEEHGYLFLRNVLDRDLVKTVAEQMREGLV
ALGAADPHATLEELTIDSFESVDEVAMHDYVKYDAFWNNPSTIKVFEQVF
GEPVFVFLSTTIRYYPSQAGSEEPSFHYLTPFHQDGFYIGPNQDFRTFWI
PLIRTTRESGGVALADGSHRRGKRDHVLNESFRRFGHPVRGIPPTEVSED
EHLLHSPMEPGDILLFHAHMCHKSIPNLSKDPRLMRMSMDTRVQPAKSHR
GFNAMTPWTES
3D structure
PDB2rds Crystal Structure of the Non-heme Iron Dioxygenase PtlH in Pentalenolactone Biosynthesis.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.35: 1-deoxypentalenic acid 11beta-hydroxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A H137 D139 H226 H133 D135 H222
BS02 1PL A R117 T134 H137 Y142 R188 R113 T130 H133 Y138 R184
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0031418 L-ascorbic acid binding
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0017000 antibiotic biosynthetic process
GO:1901336 lactone biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2rds, PDBe:2rds, PDBj:2rds
PDBsum2rds
PubMed17942405
UniProtQ82IZ1|PTLH_STRAW 1-deoxypentalenic acid 11-beta-hydroxylase (Gene Name=ptlH)

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