Structure of PDB 2rdn Chain A

Receptor sequence
>2rdnA (length=275) Species: 33903 (Streptomyces avermitilis) [Search protein sequence]
TNVTGDYTDCTPLLGDRAALDSFYEEHGYLFLRNVLDRDLVKTVAEQMRE
GLVALGAADPHATLEELTIDSFESVDEVAMHDYVKYDAFWNNPSTIKVFE
QVFGEPVFVFLSTTIRYYPSQAGSEEPSFHYLTPFHQDGFYIGPNQDFRT
FWIPLIRTTRESGGVALADGSHRRGKRDHVLNESFRRFGHPVRGIPPTEV
SEDEHLLHSPMEPGDILLFHAHMCHKSIPNLSKDPRLMRMSMDTRVQPAK
SHRGFNAMTPWTESAKDASKGIMAK
3D structure
PDB2rdn Crystal Structure of the Non-heme Iron Dioxygenase PtlH in Pentalenolactone Biosynthesis.
ChainA
Resolution1.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.35: 1-deoxypentalenic acid 11beta-hydroxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A H137 D139 H226 H136 D138 H225
BS02 AKG A R117 H137 D139 T151 W153 H226 S228 R240 D244 R246 R116 H136 D138 T150 W152 H225 S227 R239 D243 R245
BS03 1PL A R117 T134 H137 Y142 R188 A269 S270 R116 T133 H136 Y141 R187 A268 S269
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0031418 L-ascorbic acid binding
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0017000 antibiotic biosynthetic process
GO:1901336 lactone biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2rdn, PDBe:2rdn, PDBj:2rdn
PDBsum2rdn
PubMed17942405
UniProtQ82IZ1|PTLH_STRAW 1-deoxypentalenic acid 11-beta-hydroxylase (Gene Name=ptlH)

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