Structure of PDB 2rc9 Chain A

Receptor sequence
>2rc9A (length=287) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSSL
HSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNG
HWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRG
TELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPA
TPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYG
IGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVV
3D structure
PDB2rc9 Molecular mechanism of ligand recognition by NR3 subtype glutamate receptors.
ChainA
Resolution1.96 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1AC A Y97 S123 F124 S125 R130 S179 S180 M223 D224 Y94 S120 F121 S122 R127 S176 S177 M220 D221 PDBbind-CN: -logKd/Ki=7.40,IC50=0.04uM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:2rc9, PDBe:2rc9, PDBj:2rc9
PDBsum2rc9
PubMed18636091
UniProtQ9R1M7|NMD3A_RAT Glutamate receptor ionotropic, NMDA 3A (Gene Name=Grin3a)

[Back to BioLiP]