Structure of PDB 2r8t Chain A

Receptor sequence
>2r8tA (length=319) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
RRELAIEFSRVTESAALAGYKWLGRGDKNTADGAAVNAMRIMLNQVNIDG
TIVIGEGEIAEAPMLYIGEKVGTGRGDAVDIAVDPIEGTRMTAMGQANAL
AVLAVGDKGCFLNAPDMYMEKLIVGPGAKGTIDLNLPLADNLRNVAAALG
KPLSELTVTILAKPRHDAVIAEMQQLGVRVFAIPDGDVAASILTCMPDSE
VDVLYGIGGAPEGVVSAAVIRALDGDMNGRLLARHDVKENRRIGEQELAR
CKAMGIEAGKVLRLGDMARSDNVIFSATGITKGDLLEGISRKGNIATTET
LLIRGKSRTIRRIQSIHYL
3D structure
PDB2r8t Crystal structure of the fructose 1,6-bisphosphatase GlpX from E.coli in the complex with fructose 1,6-bisphosphate
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.11: fructose-bisphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FBP A E88 T90 Y119 K164 R166 D186 G187 D188 G210 E87 T89 Y118 K163 R165 D185 G186 D187 G209
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding
GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006071 glycerol metabolic process
GO:0006094 gluconeogenesis
GO:0030388 fructose 1,6-bisphosphate metabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:2r8t, PDBe:2r8t, PDBj:2r8t
PDBsum2r8t
PubMed
UniProtP0A9C9|GLPX_ECOLI Fructose-1,6-bisphosphatase 1 class 2 (Gene Name=glpX)

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