Structure of PDB 2r87 Chain A

Receptor sequence
>2r87A (length=334) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]
MKVRIATYASHSALQILKGAKDEGFETIAFGSSKVKPLYTKYFPVADYFI
EEKYPEEELLNLNAVVVPTGSFVAHLGIELVENMKVPYFGNKRVLRWESD
RNLERKWLKKAGIRVPEVYEDPDDIEKPVIVKPHGAKGGKGYFLAKDPED
FWRKAEKFLGIKRKEDLKNIQIQEYVLGVPVYPHYFYSKVREELELMSID
RRYESNVDAIGRIPAKDQLEFDMDITYTVIGNIPIVLRESLLMDVIEAGE
RVVKAAEELMGGLWGPFCLEGVFTPDLEFVVFEISARIVAGTNIFVNGSP
YTWLRYDRPVSTGRRIAMEIREAIENDMLEKVLT
3D structure
PDB2r87 Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.4.23: formate--phosphoribosylaminoimidazolecarboxamide ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A I130 K132 G138 G139 Y142 Q173 E174 Y175 V176 R202 E204 Y227 E270 F282 E283 I130 K132 G138 G139 Y142 Q173 E174 Y175 V176 R202 E204 Y227 E270 F282 E283
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016879 ligase activity, forming carbon-nitrogen bonds
GO:0046872 metal ion binding
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006188 IMP biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2r87, PDBe:2r87, PDBj:2r87
PDBsum2r87
PubMed18069798
UniProtQ8U0R7|PURP_PYRFU 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase (Gene Name=purP)

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