Structure of PDB 2r7p Chain A

Receptor sequence
>2r7pA (length=308) Species: 36435 (Simian 11 rotavirus (serotype 3 / strain SA11-Ramig)) [Search protein sequence]
AELACFCYPHLENDSYKFIPFNNLAIKAMLTAKVDKKDMDKFYDSIIYGI
APPPQFKKRYNTNDNSRGMNFETIMFTKVAMLICEALNSLKVTQANVSNV
LSRVVSIRHLENLVIRKENPQDILFHSKDLLLKSTLIAIGQSKEIETTIT
AEGGEIVFQNAAFTMWKLTYLEHQLMPILDQNFIEYKVTLNEDKPISDVH
VKELVAELRWQYNKFAVITHGKGAYRIVKYSSVANHADRVYATFKSNVKN
DFNLLDQRIIWQNWYAFTSSMKQGNTLDVCKRLLFQKMKPEKNPFKGLST
DRKMDEVS
3D structure
PDB2r7p Crystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like Activity
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 A K301 G302 S304 K296 G297 S299
BS02 ANP A S107 R109 K188 H221 K223 R227 S106 R108 K187 H220 K222 R226
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0004550 nucleoside diphosphate kinase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016817 hydrolase activity, acting on acid anhydrides
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0019079 viral genome replication
Cellular Component
GO:0030430 host cell cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2r7p, PDBe:2r7p, PDBj:2r7p
PDBsum2r7p
PubMed17804496
UniProtQ03243|NSP2_ROTSR Non-structural protein 2

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