Structure of PDB 2r6g Chain A

Receptor sequence
>2r6gA (length=371) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
ASVQLQNVTKAWGEVVVSKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAG
LETITSGDLFIGEKRMNDTPPAERGVGMVFQSYALYPHLSVAENMSFGLK
LAGAKKEVINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAE
PSVFLLDQPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLA
DKIVVLDAGRVAQVGKPLELYHYPADRFVAGFIGSPKMNFLPVKVTATAI
DQVQVELPMPNRQQVWLPVESRDVQVGANMSLGIRPEHLLPSDIADVILE
GEVQVVEQLGNETQIHIQIPSIRQNLVYRQNDVVLVEEGATFAIGLPPER
CHLFREDGTACRRLHKEPGVA
3D structure
PDB2r6g Crystal structure of a catalytic intermediate of the maltose transporter.
ChainA
Resolution2.8 Å
3D
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Enzymatic activity
Enzyme Commision number 7.5.2.1: ABC-type maltose transporter.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A W13 V18 S38 G39 G41 K42 S43 T44 Q82 Q159 H192 W12 V17 S37 G38 G40 K41 S42 T43 Q81 Q158 H191
BS02 ATP A R129 A133 S135 G137 Q138 R128 A132 S134 G136 Q137
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015423 ABC-type maltose transporter activity
GO:0016887 ATP hydrolysis activity
GO:0022857 transmembrane transporter activity
GO:0140297 DNA-binding transcription factor binding
GO:0140359 ABC-type transporter activity
Biological Process
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0034763 negative regulation of transmembrane transport
GO:0042956 maltodextrin transmembrane transport
GO:0055085 transmembrane transport
GO:1902344 negative regulation of maltose transport
GO:1904981 maltose transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:1990060 maltose transport complex
GO:1990154 enzyme IIA-maltose transporter complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2r6g, PDBe:2r6g, PDBj:2r6g
PDBsum2r6g
PubMed18033289
UniProtP68187|MALK_ECOLI Maltose/maltodextrin import ATP-binding protein MalK (Gene Name=malK)

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