Structure of PDB 2r6f Chain A

Receptor sequence
>2r6fA (length=899) Species: 272567 (Geobacillus stearothermophilus 10) [Search protein sequence]
MDKIIVKGARAHNLKNIDVEIPRGKLVVLTGLSGSGKSSLAFDTIYAEGQ
RRYVESLSAYARQFLGQMEKPDVDAIEGLSPAISIDQKTTSRNPRSTVGT
VTEIYDYLRLLFARIGRPICPTHGIEIQSQTIEQMVDRLLSYPERTKMQI
LAPIDVVVDRIIIKDGIAARLADSLETALKLADGKVVVDVIGEGELLFSE
KHACPYCGFSIGELEPRLFSFNSPFGACPDCDGLGAKLEVDLDLVIPNDE
LTLKEHAIAPWEPYYPQLLEAVCRHYGIPMDVPVKDLPKEQLDKILYGSG
GEPIYFRYTNDFGQVREQYIAFEGVIPNVERRYRETSSDYIREQMEKYMA
EQPCPTCQGYRLKKESLAVLVGGKHIGEVTAMSVTEALAFFDGLELTEKE
AQIARLILREIRDRLGFLQNVGLDYLTLSRSAGTLSGGEAQRIRLATQIG
SRLTGVLYVLDEPSIGLHQRDNDRLIATLKSMRDLGNTLIVVEHDEDTML
AADYLIDIGPGAGIHGGEVVAAGTPEEVMNDPNSLTGQYLSGKKFIPIPA
ERRRPDGRWLEVVGAREHNLKNVSVKIPLGTFVAVTGVSGSGKSTLVNEV
LYKALAQKLHRAKAKPGEHRDIRGLEHLDKVIDIDQSPIGRTPRSNPATY
TGVFDDIRDVFASTNEAKVRGYKKGRFSFNVKGGRCEACHGDGIIKIEMH
FLPDVYVPCEVCHGKRYNRETLEVTYKGKNIAEVLDMTVEDALDFFASIP
KIKRKLETLYDVGLGYMKLGQPATTLSGGEAQRVKLAAELHRRSNGRTLY
ILDEPTTGLHVDDIARLLDVLHRLVDNGDTVLVIEHNLDVIKTADYIIDL
GPEGGDRGGQIVAVGTPEEVAEVKESHTGRYLKPILERDRARMQARYEA
3D structure
PDB2r6f Crystal Structure of Bacillus stearothermophilus UvrA Provides Insight into ATP-Modulated Dimerization, UvrB Interaction, and DNA Binding.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A H12 N13 G34 S35 G36 K37 S38 S39 Y816 Q821 H12 N13 G34 S35 G36 K37 S38 S39 Y766 Q771 PDBbind-CN: -logKd/Ki=8.00,Kd=10nM
BS02 ADP A R480 H618 N619 G640 S641 G642 K643 S644 T645 R430 H568 N569 G590 S591 G592 K593 S594 T595 PDBbind-CN: -logKd/Ki=8.00,Kd=10nM
BS03 ZN A C120 H123 C250 C120 H123 C204
BS04 ZN A C274 C277 C404 C407 C228 C231 C354 C357
BS05 ZN A C736 C739 C759 C762 C686 C689 C709 C712
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0009381 excinuclease ABC activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0009432 SOS response
Cellular Component
GO:0005737 cytoplasm
GO:0009380 excinuclease repair complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2r6f, PDBe:2r6f, PDBj:2r6f
PDBsum2r6f
PubMed18158267
UniProtQ5KVB6

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