Structure of PDB 2r40 Chain A

Receptor sequence
>2r40A (length=238) Species: 7102 (Heliothis virescens) [Search protein sequence]
QELSIERLLEMESLVADPSEEFQFLRVGPDSNVPPKFRAPVSSLCQIGNK
QIAALVVWARDIPHFSQLEMEDQILLIKGSWNELLLFAIAWRSMEFLTTT
SPPQLMCLMPGMTLHRNSALQAGVGQIFDRVLSELSLKMRTLRVDQAEYV
ALKAIILLNPDVKGLKNRQEVEVLREKMFLCLDEYCRRSRSSEEGRFAAL
LLRLPALRSISLKSFEHLFFFHLVADTSIAGYIRDALR
3D structure
PDB2r40 Critical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone Receptor
ChainA
Resolution2.402 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EPH A P239 F242 L249 N287 L290 M323 L331 A339 G340 V341 F345 L435 F438 P34 F37 L44 N82 L85 M106 L114 A122 G123 V124 F128 L218 F221
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0004879 nuclear receptor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0030522 intracellular receptor signaling pathway
GO:0043401 steroid hormone receptor signaling pathway
Cellular Component
GO:0005634 nucleus

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Cellular Component
External links
PDB RCSB:2r40, PDBe:2r40, PDBj:2r40
PDBsum2r40
PubMed17848566
UniProtQ7SIF6

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