Structure of PDB 2r3y Chain A

Receptor sequence
>2r3yA (length=280) Species: 562 (Escherichia coli) [Search protein sequence]
MTPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYI
ITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTI
PINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQ
TDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLA
TKIMDKLIRDGRVIRGYIGIGGIVVNEVSPDGPAANAGIQVNDLIISVDN
KPATMDQVAEIRPGSVIPVVVLQVTIQEYP
3D structure
PDB2r3y Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.107: peptidase Do.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L124 G185 R186 Y258 I259 I261 G263 M319 V322 L83 G144 R145 Y217 I218 I220 G222 M255 V258
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2r3y, PDBe:2r3y, PDBj:2r3y
PDBsum2r3y
PubMed17938245
UniProtP0AEE3|DEGS_ECOLI Serine endoprotease DegS (Gene Name=degS)

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