Structure of PDB 2r2t Chain A

Receptor sequence
>2r2tA (length=255) Species: 11801 (Moloney murine leukemia virus) [Search protein sequence]
TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLG
IKPHIQRLLDQGILVPCQSPWNTPLLPVKKPGTNDYRPVQDLREVNKRVE
DIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWR
DPEMGISGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYV
DDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLL
KEGQR
3D structure
PDB2r2t Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A Y64 L99 R116 Y41 L76 R93
BS02 dna A L99 D114 L115 R116 G191 L76 D91 L92 R93 G168
External links
PDB RCSB:2r2t, PDBe:2r2t, PDBj:2r2t
PDBsum2r2t
PubMed18362349
UniProtP03355|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

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