Structure of PDB 2r2f Chain A

Receptor sequence
>2r2fA (length=286) [Search protein sequence]
SRISAINWNKIQDDKDLEVWNRLTSNFWLPEKVPLSNDIPAWQTLSAAEQ
QLTIRVFTGLTLLDTIQNIAGAPSLMADAITPHEEAVLSNISFMEAVHAR
SYSSIFSTLCQTKEVDAAYAWSEENPPLQRKAQIILAHYVSDEPLKKKIA
SVFLESFLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKY
QIALQKLSAIEREELKLFALDLLMELYDNEIRYTEALYAETGWVNDVKAF
LCYNANKALMNLGYEALFPPEMADVNPAILAALSPN
3D structure
PDB2r2f Structure of Salmonella typhimurium nrdF ribonucleotide reductase in its oxidized and reduced forms.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.17.4.1: ribonucleoside-diphosphate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FEO A D67 E98 H101 E158 E192 H195 D64 E95 H98 E155 E189 H192
Gene Ontology
Molecular Function
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0009263 deoxyribonucleotide biosynthetic process
Cellular Component
GO:0005971 ribonucleoside-diphosphate reductase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2r2f, PDBe:2r2f, PDBj:2r2f
PDBsum2r2f
PubMed9748343
UniProtP17424|RIR4_SALTY Ribonucleoside-diphosphate reductase 2 subunit beta (Gene Name=nrdF)

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