Structure of PDB 2r0l Chain A

Receptor sequence
>2r0lA (length=239) Species: 9606 (Homo sapiens) [Search protein sequence]
IIGGSSSLPGSHPWLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDS
VSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKG
DRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREA
LVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKN
GVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIR
3D structure
PDB2r0l Structural insight into distinct mechanisms of protease inhibition by antibodies.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S26 W29 R114 Q116 P120 C122 V206 A207 S11 W14 R106 Q108 P112 C114 V202 A203
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2r0l, PDBe:2r0l, PDBj:2r0l
PDBsum2r0l
PubMed18077410
UniProtQ04756|HGFA_HUMAN Hepatocyte growth factor activator (Gene Name=HGFAC)

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