Structure of PDB 2qz4 Chain A

Receptor sequence
>2qz4A (length=223) Species: 9606 (Homo sapiens) [Search protein sequence]
MGVSFKDVAGMHEAKLEVREFVDYLKSPEAKVPKGALLLGPPGCGKTLLA
KAVATEAQVPFLAMAGAEFVEVIGGLGAARVRSLFKEARARAPCIVYIDE
IEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFID
LPTLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEA
ALHVHTLNFEYAVERVLAGTAKK
3D structure
PDB2qz4 Crystal Structure of the ATPase Domain of the Human AAA+ Protein Paraplegin/SPG7.
ChainA
Resolution2.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.-
3.6.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A A312 G352 C353 G354 K355 T356 L357 H492 G518 A519 A9 G43 C44 G45 K46 T47 L48 H164 G190 A191
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:2qz4, PDBe:2qz4, PDBj:2qz4
PDBsum2qz4
PubMed19841671
UniProtQ9UQ90|SPG7_HUMAN Mitochondrial inner membrane m-AAA protease component paraplegin (Gene Name=SPG7)

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