Structure of PDB 2qyq Chain A

Receptor sequence
>2qyqA (length=186) Species: 9606 (Homo sapiens) [Search protein sequence]
MPVDLSKWSGPLSLQEVDEQPQHPLHVTYAGAAVDELGKVLTPTQVKNRP
TSISWDGLDSGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSG
TVLSDYVGSGPPKGTGLHRYVWLVYEQDRPLKCDEPILSNRSGDHRGKFK
VASFRKKYELRAPVAGTCYQAEWDDYVPKLYEQLSG
3D structure
PDB2qyq Phosphotyrosine recognition by the Raf Kinase Inhibitor Protein
ChainA
Resolution1.948 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PTR A D70 W84 H86 G110 H118 Y120 Y181 L184 D70 W84 H86 G110 H118 Y120 Y181 L184
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008289 lipid binding
GO:0008429 phosphatidylethanolamine binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
Biological Process
GO:0010466 negative regulation of peptidase activity
GO:0043409 negative regulation of MAPK cascade
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular exosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:2qyq, PDBe:2qyq, PDBj:2qyq
PDBsum2qyq
PubMed
UniProtP30086|PEBP1_HUMAN Phosphatidylethanolamine-binding protein 1 (Gene Name=PEBP1)

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