Structure of PDB 2qxv Chain A

Receptor sequence
>2qxvA (length=352) Species: 10090 (Mus musculus) [Search protein sequence]
FKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGE
IRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQ
CIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGG
VEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYN
FISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMED
DIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYV
WDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWD
RL
3D structure
PDB2qxv Structural basis of EZH2 recognition by EED
ChainA
Resolution1.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W102 S104 E106 D108 V111 L134 Y153 S158 P160 R200 L245 L307 G308 D309 L310 F364 W365 Q366 L383 V385 E386 R412 W22 S24 E26 D28 V31 L54 Y73 S78 P80 R120 L165 L227 G228 D229 L230 F284 W285 Q286 L303 V305 E306 R332
External links
PDB RCSB:2qxv, PDBe:2qxv, PDBj:2qxv
PDBsum2qxv
PubMed17937919
UniProtQ921E6|EED_MOUSE Polycomb protein EED (Gene Name=Eed)

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