Structure of PDB 2qxf Chain A

Receptor sequence
>2qxfA (length=433) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
QQSTFLFHDYETFGTHPALDRPAQFAAIRTDSEFNVIGEPEVFYCKPADD
YLPQPGAVLITGITPQEARAKGENEAAFAARIHSLFTVPKTCILGYNNVR
FDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPE
NDDGLPSFRLEHLTKANGIEHSDAMADVYATIAMAKLVKTRQPRLFDYLF
THRNKHKLMALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAV
IMVDLAGDISPLLELDAVPVKLVHINKCPVLAQANTLRPEDADRLGINRQ
HCLDNLKILRENPQVREKVDNVDAQLYNGFFSDADRAAMKIVLETEPRNL
PALDITFVDKRIEKLLFNYRARNFPGTLDYAEQQRWLEHRRQVFTPEFLQ
GYADELQMLVQQYADDKEKVALLKALWQYADEI
3D structure
PDB2qxf Structure of Escherichia coli exonuclease I in complex with thymidine 5'-monophosphate.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.11.1: exodeoxyribonuclease I.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A E17 D186 E11 D177
BS02 TMP A E17 T18 T21 A63 I66 T67 F107 R165 E11 T12 T15 A57 I60 T61 F101 R159
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0004527 exonuclease activity
GO:0004529 DNA exonuclease activity
GO:0005515 protein binding
GO:0008310 single-stranded DNA 3'-5' DNA exonuclease activity
GO:0046872 metal ion binding
GO:0051575 5'-deoxyribose-5-phosphate lyase activity
Biological Process
GO:0006259 DNA metabolic process
GO:0006274 DNA replication termination
GO:0006281 DNA repair
GO:0006308 DNA catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2qxf, PDBe:2qxf, PDBj:2qxf
PDBsum2qxf
PubMed18219121
UniProtP04995|EX1_ECOLI Exodeoxyribonuclease I (Gene Name=sbcB)

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