Structure of PDB 2qv7 Chain A

Receptor sequence
>2qv7A (length=303) Species: 282458 (Staphylococcus aureus subsp. aureus MRSA252) [Search protein sequence]
GSHMMRKRARIIYNPTSGKEQFKRELPDALIKLEKAGYETSAYATEKIGD
ATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVN
DFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQGP
FAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLV
PDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAIN
ISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVD
DNL
3D structure
PDB2qv7 Analysis of the Staphylococcus aureus DgkB Structure Reveals a Common Catalytic Mechanism for the Soluble Diacylglycerol Kinases.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.107: diacylglycerol kinase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A K213 D216 Y218 K204 D207 Y209
BS02 ADP A N10 T12 T41 E42 I44 G67 G69 T70 E73 G93 T94 N14 T16 T45 E46 I48 G71 G73 T74 E77 G97 T98 PDBbind-CN: -logKd/Ki=3.66,Kd=219uM
Gene Ontology
Molecular Function
GO:0004143 ATP-dependent diacylglycerol kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0008654 phospholipid biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005886 plasma membrane

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Cellular Component
External links
PDB RCSB:2qv7, PDBe:2qv7, PDBj:2qv7
PDBsum2qv7
PubMed18611377
UniProtQ6GFF9|DAGK_STAAR Diacylglycerol kinase (Gene Name=dagK)

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