Structure of PDB 2qv1 Chain A

Receptor sequence
>2qv1A (length=151) Species: 3052230 (Hepacivirus hominis) [Search protein sequence]
VEGEVQIMSTATQTFLATCINGVCWTVYHGAGTRTIASPKGPVIQMYTNV
DQDLVGWPAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLS
PRPISYLKGSSGGPLLCPAGHAVGLFRAAVCTRGVAKAVDFIPVENLETT
M
3D structure
PDB2qv1 Phenotypic and Structural Analyses of HCV NS3 Protease Val36 Variants
ChainA
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H83 D107 G163 S165
Catalytic site (residue number reindexed from 1) H29 D53 G109 S111
Enzyme Commision number 3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V55 E56 G57 E58 V59 Q60 I61 M62 S63 R88 T89 I90 A91 W111 G116 V1 E2 G3 E4 V5 Q6 I7 M8 S9 R34 T35 I36 A37 W57 G62
BS02 ZN A C123 C125 C171 C69 C71 C117
Gene Ontology
Molecular Function
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0019087 transformation of host cell by virus

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Molecular Function
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Biological Process
External links
PDB RCSB:2qv1, PDBe:2qv1, PDBj:2qv1
PDBsum2qv1
PubMed
UniProtA1Z093

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