Structure of PDB 2qry Chain A

Receptor sequence
>2qryA (length=308) Species: 562 (Escherichia coli) [Search protein sequence]
KPVLTVYTYDSFAADWGPGPVVKKAFEADCNCELKLVALEDGVSLLNRLR
MEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVAADAVNVPGGWNNDTFV
PFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRTSTPGLGLL
LWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
PAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVS
PAFQNAIPTGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWI
SEWQRAVS
3D structure
PDB2qry Structural Similarities between Thiamin-Binding Protein and Thiaminase-I Suggest a Common Ancestor
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TPS A Y27 D59 G60 S161 T162 P163 W197 Y215 S218 E245 N279 M281 Y9 D41 G42 S143 T144 P145 W179 Y197 S200 E227 N261 M263 MOAD: Kd=2.3nM
PDBbind-CN: -logKd/Ki=8.64,Kd=2.3nM
BindingDB: Kd=2.3nM
Gene Ontology
Molecular Function
GO:0030975 thiamine binding
GO:0030976 thiamine pyrophosphate binding
Biological Process
GO:0015888 thiamine transport
GO:0055085 transmembrane transport
GO:0071934 thiamine transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2qry, PDBe:2qry, PDBj:2qry
PDBsum2qry
PubMed18177053
UniProtP31550|THIB_ECOLI Thiamine-binding periplasmic protein (Gene Name=thiB)

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