Structure of PDB 2qpy Chain A

Receptor sequence
>2qpyA (length=248) Species: 10090 (Mus musculus) [Search protein sequence]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIA
RELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
3D structure
PDB2qpy A surface on the androgen receptor that allosterically regulates coactivator binding.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V716 K720 Q733 M734 Q738 M894 V46 K50 Q63 M64 Q68 M224
BS02 DHT A L704 N705 M745 M749 F764 T877 L34 N35 M75 M79 F94 T207 BindingDB: EC50=3.98nM,IC50=1.000000nM
BS03 4HY A G724 N727 F826 L830 N833 Y834 R840 G54 N57 F156 L160 N163 Y164 R170
External links
PDB RCSB:2qpy, PDBe:2qpy, PDBj:2qpy
PDBsum2qpy
PubMed17911242
UniProtP19091|ANDR_MOUSE Androgen receptor (Gene Name=Ar)

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